Package 'ClinicalVariantR'

Title: Clinical Variant Interpretation Using ACMG/AMP Germline Criteria
Description: ClinicalVariantR is an interactive Shiny platform for evidence-based germline variant classification under ACMG/AMP 2015 guidelines. It accepts VEP-, SnpEff-, or ANNOVAR-annotated VCF files and applies automated plus curator-guided ACMG criteria. The package supports streaming analysis of large call sets and exports structured per-criterion evidence with reproducibility metadata for clinical review.
Authors: Safa Rafique [aut, cre] (ORCID: <https://orcid.org/0000-0003-2646-8106>), Naeem Mahmood [aut], Muhammad Farooq Sabar [aut]
Maintainer: Safa Rafique <[email protected]>
License: MIT + file LICENSE
Version: 0.99.3
Built: 2026-09-30 09:33:37 UTC
Source: https://github.com/BiocStaging/ClinicalVariantR

Help Index

Build the ClinicalVariantR Shiny application

Description

Returns a Shiny app object for ACMG/AMP germline variant classification. Following Bioconductor Shiny guidelines, this function returns the app and does not launch it. Call shiny::runApp() yourself.

Usage

ClinicalVariantR(...)

Arguments

...

Reserved for future options (currently ignored).

Value

A shiny.appobj created by shiny::shinyApp().

See Also

ClinicalVariantRApp

Examples

stopifnot(is.function(ClinicalVariantR))
stopifnot(is.function(ClinicalVariantRApp))

Alias for ClinicalVariantR

Description

Alias for ClinicalVariantR

Usage

ClinicalVariantRApp(...)

Arguments

...

Reserved for future options (currently ignored).

Value

A shiny.appobj created by shiny::shinyApp().

Examples

stopifnot(is.function(ClinicalVariantRApp))