To cite DgeaHeatmap in publications use:
Lancelle LJ, Potru PS, Spittau B, Wiemann S (2025). “DgeaHeatmap: an R package for transcriptomic analysis and heatmap generation.” Bioinformatics Advances, 5(1), vbaf194. ISSN 2635-0041. doi:10.1093/bioadv/vbaf194. https://doi.org/10.1093/bioadv/vbaf194.
Corresponding BibTeX entry:
@Article{,
title = {DgeaHeatmap: an R package for transcriptomic analysis and
heatmap generation},
author = {Leonie J Lancelle and Phani S Potru and Bjoern Spittau
and Susanne Wiemann},
journal = {Bioinformatics Advances},
volume = {5},
number = {1},
pages = {vbaf194},
year = {2025},
month = {08},
issn = {2635-0041},
abstract = {The growing use of transcriptomic data from platforms
like Nanostring GeoMx DSP demands accessible and flexible tools
for differential gene expression analysis and heatmap generation.
Current web-based tools often lack transparency, modifiability,
and independence from external servers creating barriers for
researchers seeking customizable workflows, as well as data
privacy and security. Additionally, tools that can be utilized by
individuals with minimal bioinformatics expertise provide an
inclusive solution, empowering a broader range of users to
analyze complex data effectively.Here, we introduce Differential
Gene Expression Analysis and Heatmaps (DgeaHeatmap), an R package
offering streamlined and user-friendly functions for
transcriptomic data analysis particularly yielded by Nanostring
GeoMx DSP instruments. The package supports both normalized and
raw count data, providing tools to preprocess, filter, and
annotate datasets. DgeaHeatmap leverages Z-score scaling and
k-means clustering for customizable heatmap generation and
incorporates a workflow adapted from GeoMxTools for handling raw
Nanostring GeoMx DSP data. By enabling server-independent
analyses, the package enhances flexibility, transparency, and
reproducibility in transcriptomic research.The package
DgeaHeatmap is freely available on GitLab
(https://gitlab.ub.uni-bielefeld.de/spittaulab/Dgea/Heatmap/Package.git).},
doi = {10.1093/bioadv/vbaf194},
url = {https://doi.org/10.1093/bioadv/vbaf194},
}