Changes in version 0.99.0                        

New features

  - Initial Bioconductor submission.
  - Added methods for estimating longitudinal molecular trajectories
    using empirical, linear mixed-effects, generalized additive model
    (GAM), and maSigPro estimators.
  - Introduced Omics Trajectory Signatures (OTS) for classifying
    temporal molecular behaviour.
  - Implemented topology-aware clustering and cluster evaluation
    utilities.
  - Added a flexible topology-based query framework for retrieving
    molecular features matching simple or complex trajectory patterns
    across experimental groups and treatment arms.
  - Included publication-quality visualisation functions for
    trajectories, topology composition, and cluster summaries.
  - Added comprehensive documentation, runnable examples, unit tests,
    and vignettes.