Package: MacrophageFramework
Type: Package
Title: Multidimensional Macrophage Profiling
Version: 0.99.0
Authors@R: 
    person(
        "Alessandro", "Palma",
        email = "alessandro.palma2@uniroma1.it",
        role = c("aut", "cre", "cph"),
        comment = c(ORCID = "0000-0003-1300-5479")
    )
Description: Provides a multidimensional computational framework for
        macrophage profiling based on an ontology of biological
        programs. The framework independently detects macrophage
        populations and characterizes their lineage-associated and
        functional-state programs using program-level expression
        scores, detection coverage, gene-program coherence, cluster
        profiles, and profile similarity. The framework is designed to
        capture continuous and combinatorial macrophage states without
        imposing binary activation categories.
License: GPL-3
URL: https://github.com/AlessandroPalma-hub/MacrophageFramework
BugReports: https://github.com/AlessandroPalma-hub/MacrophageFramework/issues
Encoding: UTF-8
Depends: R (>= 4.5.0)
Imports: ggplot2, Matrix, patchwork, Seurat, SeuratObject
Suggests: testthat (>= 3.0.0), knitr, rmarkdown
VignetteBuilder: knitr
Config/testthat/edition: 3
biocViews: GeneExpression, ImmunoOncology, SingleCell, Software,
        Visualization
RoxygenNote: 8.0.0
Config/pak/sysreqs: cmake libglpk-dev make libicu-dev libpng-dev
        libuv1-dev libxml2-dev libssl-dev python3 zlib1g-dev
Repository: https://biocstaging.r-universe.dev
Date/Publication: 2026-10-26 15:15:27 UTC
RemoteUrl: https://github.com/BiocStaging/MacrophageFramework
RemoteRef: HEAD
RemoteSha: 34082803510846696ed9fb860eee3dd83ccdd629
NeedsCompilation: no
Packaged: 2026-10-26 19:35:17 UTC; root
Author: Alessandro Palma [aut, cre, cph] (ORCID:
    <https://orcid.org/0000-0003-1300-5479>)
Maintainer: Alessandro Palma <alessandro.palma2@uniroma1.it>