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# CITATION.cff file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "RPBC" in publications use:'
type: software
license: MIT
title: 'RPBC: Region-Preserving Batch Correction for Paired Region-Resolved Single-Cell
  Data'
version: 0.99.0
abstract: Implements Region-Preserving Batch Correction (RPBC), an empirical-Bayes
  location-scale framework for paired region-resolved single-cell and spatial-omics
  data. RPBC preserves a patient-balanced population-average regional contrast while
  harmonizing patient-wide location shifts, patient-specific regional deviations,
  and patient-region scale heterogeneity. The package also provides Adaptive RPBC
  for group-size-dependent stabilization of patient-region scale variation and covariate-adjusted
  RPBC for preserving prespecified patient-level covariate-associated variation during
  harmonization. RPBC is designed to interoperate with Bioconductor data structures
  for single-cell and spatial experiments.
authors:
- family-names: Amona
  given-names: Elizabeth B.
  email: amonaelizabeth1@gmail.com
  orcid: https://orcid.org/0000-0002-7575-788X
repository: https://biocstaging.r-universe.dev
commit: 8db3a51a4014c1fffe88f70994e83ab089ef9a40
date-released: '2026-10-12'
contact:
- family-names: Amona
  given-names: Elizabeth B.
  email: amonaelizabeth1@gmail.com
  orcid: https://orcid.org/0000-0002-7575-788X