NEWS

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TweedSpot 0.99.1

• Added SCRAN-based size factor estimation through size_factor_method = "scran", while preserving total-count library-size scaling as size_factor_method = "library_size".
• Added tweedie_p support for mgcv-compatible variance power settings: estimated Tweedie, Gaussian, Poisson, fixed Tweedie powers in (1, 2], and inverse Gaussian for strictly positive responses.
• Removed Stouffer p-value combination from the two-part model interface.

TweedSpot 0.99.0

• Initial Bioconductor-oriented development release.
• Added agnostic spatially variable gene detection with Tweedie GAMs.
• Added gene filtering, result extraction, ranking helpers, and spatial plotters.