{
  "_id": "6aade6753d719c1f840783ce",
  "Package": "cascadeR",
  "Title": "Shiny App to Explore Single-Cell Analysis",
  "Version": "0.99.0",
  "Authors@R": "c(\nperson(\"Apratim\", \"Mitra\", , \"apratim.mitra@gmail.com\",\nrole = c(\"aut\", \"cre\"), comment = c(ORCID = \"0000-0003-3279-0054\")),\nperson(\"Ryan\", \"Dale\", , \"ryan.dale@nih.gov\",\nrole = c(\"fnd\"), comment = c(ORCID = \"0000-0003-2664-3744\"))\n)",
  "Description": "Interactive and modular shiny app for single-cell and\nspatial transcriptomic data exploration and management.\nVisualize cell clusters or groups using interactive cell\nembeddings, e.g. UMAP or t-SNE, or spatial views. Explore cell\ncomposition and quality control metrics using the metadata\nviewer module. Investigate the effect of clustering resolutions\nor compare annotation sources using cluster tree. Visualize\ngene expression using cell embeddings or in spatial context\nwith feature plots and coexpression plots or in cell clusters\nusing dotplots, violin plots. Manage marker tables from\nsingle-cell or pseudo-bulk analyses and track genes of interest\nusing the gene scratchpad. Choose interesting cells with lasso\nselection directly from interactive plots and export for\ndownstream analysis. Slice and dice datasets with custom\nfilters based on cell metadata, gene expression or lasso\nselections. Efficiently handle large datasets using custom\ndownsampling controls. CascadeR has cross-ecosystem\ncompatibility with support for Seurat, SingleCellExperiment and\nAnnData objects. In addition, the app includes an integrated\nplatform to manage multiple projects and user access that can\nbe run on a central server to share with collaborators.",
  "License": "MIT + file LICENSE",
  "Encoding": "UTF-8",
  "Roxygen": "list(markdown = TRUE)",
  "VignetteBuilder": "knitr",
  "BugReports": "https://github.com/NICHD-BSPC/cascadeR/issues",
  "biocViews": "Software, SingleCell, Spatial, Transcriptomics,\nGeneExpression, Visualization, DifferentialExpression,\nShinyApps, GUI",
  "URL": "https://nichd-bspc.github.io/cascadeR/",
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  "Repository": "https://biocstaging.r-universe.dev",
  "Date/Publication": "2026-09-18 22:52:46 UTC",
  "RemoteUrl": "https://github.com/BiocStaging/cascadeR",
  "RemoteRef": "HEAD",
  "RemoteSha": "3c944e1f7344b998eb09c0419f7bc952ec862347",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-09-19 01:24:54 UTC",
    "User": "root"
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  "Author": "Apratim Mitra [aut, cre] (ORCID:\n<https://orcid.org/0000-0003-3279-0054>),\nRyan Dale [fnd] (ORCID: <https://orcid.org/0000-0003-2664-3744>)",
  "Maintainer": "Apratim Mitra <apratim.mitra@gmail.com>",
  "_user": "biocstaging",
  "_type": "src",
  "_file": "cascadeR_0.99.0.tar.gz",
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  "_expires": "2026-12-28T01:33:39.000Z",
  "_created": "2026-09-19T01:24:54.000Z",
  "_published": "2026-09-19T01:33:41.512Z",
  "_bioccheck": {
    "error": 0,
    "warning": 0,
    "note": 8
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  "_host": "GitHub-Actions",
  "_buildurl": "https://github.com/r-universe/biocstaging/actions/runs/35412314297",
  "_status": "success",
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  "_commit": {
    "id": "3c944e1f7344b998eb09c0419f7bc952ec862347",
    "author": "Apratim Mitra <16709900+mitraak@users.noreply.github.com>",
    "committer": "GitHub <noreply@github.com>",
    "message": "Merge pull request #4 from NICHD-BSPC/bioc_prep\n\nPrepare for bioc submissionFinalize package for bioc submission:\n\n- add tests\n- add function examples\n- misc feature updates\n  - downsampling for plotting large data\n  - restyle to show scatter plot selections\n- add pkdown for github.io pages\n- add support for `SingleCellExperiment`\n- add vignette(s)\n- wired up new centralized selection handling to filter module\n- added 'delete filter' option in filter module  ",
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    "get_project_name_from_path",
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    "markerPlotServer",
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    "markerTableGeneralUI",
    "markerTableServer",
    "markerTableUI",
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    "save_access_yaml",
    "scatterPlotServer",
    "scatterPlotUI",
    "selectionServer",
    "selectionUI",
    "settingsServer",
    "settingsUI",
    "spatialCoexpressionPlotServer",
    "spatialCoexpressionPlotUI",
    "spatialFeaturePlotServer",
    "spatialFeaturePlotUI",
    "subsetServer",
    "subsetUI",
    "summaryServer",
    "summaryUI",
    "umap_ly",
    "violin2",
    "violinServer",
    "violinUI"
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      "title": "Add new cascade analysis",
      "topics": [
        "add_cascade_analysis"
      ]
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      "title": "Generalized version of Seurat:::BlendExpression",
      "topics": [
        "BlendExpression2"
      ]
    },
    {
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      "title": "Interactive blend map plot",
      "topics": [
        "BlendMap2"
      ]
    },
    {
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      "title": "Build cluster tree for anndata objects",
      "topics": [
        "BuildClusterTree2"
      ]
    },
    {
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      "title": "Get data areas a user has access to",
      "topics": [
        "check_user_access"
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    },
    {
      "page": "clustreemod",
      "title": "Cluster tree module",
      "topics": [
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        "clustreeServer",
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    },
    {
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      "title": "Metadata viewer module",
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        "clustSummaryServer",
        "clustSummaryUI"
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      "title": "Coexpression plot module",
      "topics": [
        "coexpmod",
        "coexpressionPlotServer",
        "coexpressionPlotUI"
      ]
    },
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      "page": "controlmod",
      "title": "Filter control module",
      "topics": [
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        "controlServer",
        "controlUI"
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    },
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      "title": "Create access yaml",
      "topics": [
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    },
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      "title": "Cell embeddings module",
      "topics": [
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        "dimredServer",
        "dimredUI"
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    },
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      "title": "Download file module",
      "topics": [
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        "downloadFileServer",
        "downloadFileUI"
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    },
    {
      "page": "dlmod",
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        "downloadPlotUI"
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      "title": "Dotplot",
      "topics": [
        "dotplot"
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      "page": "dotplotmod",
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      "topics": [
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        "dotPlotServer",
        "dotPlotUI"
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    },
    {
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      "title": "Binned coexpression plot for 2 features",
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    },
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      "title": "Interactive feature plot",
      "topics": [
        "feature_ly"
      ]
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      "title": "Feature plot module",
      "topics": [
        "featurePlotServer",
        "featurePlotUI",
        "ftrpltmod"
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    },
    {
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      "title": "Get path to access yaml",
      "topics": [
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    },
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      "title": "Bin gene expression in columns of a data frame",
      "topics": [
        "get_binned_exp"
      ]
    },
    {
      "page": "get_coexp_legend",
      "title": "Function to generate coexpression plot legend",
      "topics": [
        "get_coexp_legend"
      ]
    },
    {
      "page": "get_coexp_tbl",
      "title": "Get counts table based on coexpression",
      "topics": [
        "get_coexp_tbl"
      ]
    },
    {
      "page": "get_coexplt_colors",
      "title": "Function to return coexpression plot colormaps",
      "topics": [
        "get_coexplt_colors"
      ]
    },
    {
      "page": "get_config",
      "title": "Get config",
      "topics": [
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    },
    {
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      "title": "Get plotly label trace",
      "topics": [
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    {
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      "title": "Get limits of numeric vector",
      "topics": [
        "get_limits"
      ]
    },
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      "title": "Get project name from path",
      "topics": [
        "get_project_name_from_path"
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    },
    {
      "page": "get_var_genes",
      "title": "Get highly variable genes",
      "topics": [
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    },
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      "page": "helpmod",
      "title": "Help button module",
      "topics": [
        "helpButtonServer",
        "helpButtonUI",
        "helpmod"
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    },
    {
      "page": "helpModal",
      "title": "Help modal",
      "topics": [
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    },
    {
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      "title": "Create cascade python environment",
      "topics": [
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    },
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      "title": "Line plot module",
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        "linemod",
        "linePlotServer",
        "linePlotUI"
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      "title": "Create a tiny example Seurat object",
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      "title": "Marker plots module",
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        "markerPlotServer",
        "markerPlotUI",
        "markerpltmod"
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    },
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      "title": "Generalized marker table module",
      "topics": [
        "markertablegeneralmod",
        "markerTableGeneralServer",
        "markerTableGeneralUI"
      ]
    },
    {
      "page": "markertablemod",
      "title": "Marker tables module",
      "topics": [
        "markertablemod",
        "markerTableServer",
        "markerTableUI"
      ]
    },
    {
      "page": "PseudoBulkExpression2",
      "title": "Get pseudobulk expression from anndata object",
      "topics": [
        "PseudoBulkExpression2"
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    {
      "page": "read_access_yaml",
      "title": "Read access yaml with user groups and data areas",
      "topics": [
        "read_access_yaml"
      ]
    },
    {
      "page": "run_cascade",
      "title": "Cascade",
      "topics": [
        "run_cascade"
      ]
    },
    {
      "page": "sanitize_colnames",
      "title": "Sanitize strings",
      "topics": [
        "sanitize_colnames"
      ]
    },
    {
      "page": "save_access_yaml",
      "title": "Save access yaml to file",
      "topics": [
        "save_access_yaml"
      ]
    },
    {
      "page": "scattermod",
      "title": "Gene-gene scatter plot module",
      "topics": [
        "scattermod",
        "scatterPlotServer",
        "scatterPlotUI"
      ]
    },
    {
      "page": "selmod",
      "title": "Download selection module",
      "topics": [
        "selectionServer",
        "selectionUI",
        "selmod"
      ]
    },
    {
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      "title": "Settings module",
      "topics": [
        "settingsmod",
        "settingsServer",
        "settingsUI"
      ]
    },
    {
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      "title": "Spatial coexpression plot module",
      "topics": [
        "spatialcoexpmod",
        "spatialCoexpressionPlotServer",
        "spatialCoexpressionPlotUI"
      ]
    },
    {
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      "title": "Spatial feature plot module",
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        "spatialftrpltmod"
      ]
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        "violin2"
      ]
    },
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      "title": "Violin plot module",
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        "violinServer",
        "violinUI"
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