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  "Package": "postexportKinetics",
  "Title": "Kinetic Model Comparison for Post-Export RNA Conversion",
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  "Description": "Compartment-resolved four-state kinetic modelling of\nnuclear and cytoplasmic, unprocessed and processed RNA.\nImplements a constrained nested-model comparison between a null\nmodel without a post-export conversion rate and a full model\nwith a non-negative post-export conversion rate, using\ntrapezoidal interval balances, propagated and regularised\nmeasurement covariance, whitened non-negative least squares and\na replicate-level generative bootstrap with an add-one p-value.\nAlso provides simulation with the manuscript simulator and\nassay-noise models, diagnostic comparison of sampling designs\nwith the manuscript benchmark, multiple-testing adjustment,\nexploratory candidate ranking, tidy result tables and plots.\nThe post-export conversion rate is a phenomenological parameter\nand does not identify a specific molecular mechanism.",
  "License": "MIT + file LICENSE",
  "URL": "https://github.com/bioinformatics-sannio/postexportKinetics",
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  "Date/Publication": "2026-09-26 11:05:44 UTC",
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