Package: bppg Title: Bipartite peptide-protein graphs Version: 0.99.1 Date: 2026-08-12 Authors@R: c( person("Karin", "Schork", , "karin.schork@rub.de", role = c("aut", "cre"), comment = c(ORCID = "0000-0003-3756-4347")), person("Julika", "Wenzel", , "julika.wenzel@rub.de", role = c("aut"), comment = c(ORCID = "0009-0004-1468-5984")), person("Katharina", "Neuhaus", , "katharina.neuhaus@rub.de", role = c("aut")), person("Martin", "Eisenacher", , "martin.eisenacher@rub.de", role = c("aut", "fnd"), comment = c(ORCID = "0000-0003-2687-7444"))) Description: This package contains functionality to create and characterize bipartite graphs that model the relationship between peptides and proteins in bottom-up proteomics. With these graphs, protein ratios (fold change between two sample groups) are calculated from the respective measured peptide ratios. The main aim is to make use of quantitative information contained in shared peptides and making it possible to quantify proteins without shared peptides. Further, the package offers general analysis of peptide and protein relationships using bipartite graphs and visualization for these graphs. License: BSD_3_clause + file LICENSE Encoding: UTF-8 Roxygen: list(markdown = TRUE) biocViews: Proteomics, GraphAndNetwork, MassSpectrometry, MultipleComparison, Visualization Imports: checkmate, ggplot2, ggraph, limma, openxlsx, pbapply, robustbase, Rsolnp, stringr, SummarizedExperiment, vsn Suggests: covr, rmarkdown, testthat (>= 3.0.0), tidySummarizedExperiment, seqinr, BiocStyle, knitr, pak, RefManageR, sessioninfo, batchtools Config/testthat/edition: 3 VignetteBuilder: knitr Depends: R (>= 3.5.0), igraph (>= 2.0.0) Config/roxygen2/version: 8.1.0 URL: https://github.com/mpc-bioinformatics/bppg BugReports: https://github.com/mpc-bioinformatics/bppg/issues Config/pak/sysreqs: libfontconfig1-dev libfreetype6-dev libglpk-dev libicu-dev libxml2-dev zlib1g-dev Repository: https://biocstaging.r-universe.dev Date/Publication: 2026-08-12 12:14:48 UTC RemoteUrl: https://github.com/BiocStaging/bppg RemoteRef: HEAD RemoteSha: e3f64d0f75108a1114b1ab00d2e1b34c0b657f81 NeedsCompilation: no Packaged: 2026-10-11 10:05:25 UTC; root Author: Karin Schork [aut, cre] (ORCID: ), Julika Wenzel [aut] (ORCID: ), Katharina Neuhaus [aut], Martin Eisenacher [aut, fnd] (ORCID: ) Maintainer: Karin Schork