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# CITATION.cff file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "dmsa" in publications use:'
type: software
license: MIT
title: 'dmsa: Directional Methylation Set Analysis'
version: 0.99.11
doi: 10.32614/CRAN.package.dmsa
abstract: Aligns probe-level methylation effects to their predicted effect on gene
  expression and, for system-level analysis, to each gene's curated polarity with
  respect to the system's activation tone (e.g. NR3C1 opposes HPA-axis activation).
  Pools the aligned coefficients with fixed-sign or expected-sign estimators and reports
  coverage and activation/brake balance per set. Ships the Project Alpha gene-system
  map, a gene-to-system polarity table carrying a stated source and review flag on
  every row, and a curated system > module > gene > probe selection cascade whose
  module labels carry literature-audited evidence tiers and citations; genes without
  a polarity entry must be specified by the user.
authors:
- family-names: Ein-Dor
  given-names: Tsachi
  email: teindor@runi.ac.il
  orcid: https://orcid.org/0000-0002-3078-7591
repository: https://biocstaging.r-universe.dev
repository-code: https://github.com/teindor/dmsa
commit: 958def1e80f29396dba951b9de03d547f9f22935
url: https://teindor.github.io/dmsa
date-released: '2026-09-03'
contact:
- family-names: Ein-Dor
  given-names: Tsachi
  email: teindor@runi.ac.il
  orcid: https://orcid.org/0000-0002-3078-7591