Package: exploreDE Type: Package Title: Interactive Exploration of Differential Expression Results Version: 0.99.0 Authors@R: c( person("Peter", "Leary", email = "peter.leary@uzh.ch", role = "aut", comment = c(ORCID = "0000-0003-1430-6185")), person("Witold", "Wolski", email = "wewolski@gmail.com", role = "cre", comment = c(ORCID = "0000-0002-6468-120X")), person("Functional Genomics Center Zurich", role = "fnd")) Description: A Shiny application to help users explore and enjoy their 'omics data, and make publication-quality figures. It shows differential expression results from RNA-seq, proteomics and CRISPR screens as ordination plots, heatmaps, volcano plots, box plots, GO and KEGG pathway views, and ORA and GSEA tables. The app reads AnnData ('.h5ad') files in the exploreDE/1.0 layout, which build_explore_h5ad() writes from counts, sample tables, DE tables and enrichment results, and the SummarizedExperiment results of the FGCZ SUSHI and prolfqua pipelines. App settings are saved and restored as JSON session files. License: MIT + file LICENSE URL: https://fgcz.github.io/exploreDE/, https://github.com/fgcz/exploreDE BugReports: https://github.com/fgcz/exploreDE/issues biocViews: Software, ShinyApps, GUI, Visualization, DifferentialExpression, GeneExpression, RNASeq, Transcriptomics, Proteomics, CRISPR, GeneSetEnrichment, Pathways, GO, KEGG Encoding: UTF-8 Depends: R (>= 4.5.0) Imports: shiny, shinydashboard, ggpubr, plotly, DESeq2, RColorBrewer, ComplexHeatmap, clusterProfiler, DT, colourpicker, circlize, kableExtra, ggrepel, sortable, waiter, ggprism, ggbeeswarm, rstatix, parallel, shinyjs, shinycssloaders, GGally, Matrix, fresh, scuttle, qs2, vegan, limma, officer, R6, anndataR (>= 1.2.3), rhdf5, jsonlite, curl, SummarizedExperiment, S4Vectors, dplyr, ggplot2, gtools, matrixStats, methods, openxlsx, readr, tibble, xml2, dendextend, rlang, colorspace, cowplot, enrichplot, ggvenn, scales, tidyr, stats, utils, grDevices, graphics Suggests: BiocManager, png, ggtext, gridtext, glmpca, pathview, KEGGREST, DOSE, testthat (>= 3.0.0), shinytest2, callr, jsonvalidate, systemfonts, ragg, nanoparquet, arrow, knitr, rmarkdown, BiocStyle, withr, devtools VignetteBuilder: knitr Config/testthat/edition: 3 Roxygen: list(markdown = TRUE) Config/roxygen2/version: 8.1.1 Config/pak/sysreqs: cmake libfontconfig1-dev libfreetype6-dev libfribidi-dev libglpk-dev make libharfbuzz-dev libicu-dev libjpeg-dev libpng-dev libtiff-dev libuv1-dev libwebp-dev libxml2-dev libssl-dev perl python3 libx11-dev zlib1g-dev Repository: https://biocstaging.r-universe.dev Date/Publication: 2026-11-14 18:03:32 UTC RemoteUrl: https://github.com/BiocStaging/exploreDE RemoteRef: HEAD RemoteSha: 0a0839713a11b83aecac2e7b0cc3bbc4543f1398 NeedsCompilation: no Packaged: 2026-11-14 18:58:10 UTC; root Author: Peter Leary [aut] (ORCID: ), Witold Wolski [cre] (ORCID: ), Functional Genomics Center Zurich [fnd] Maintainer: Witold Wolski