Package: karioCaS Title: Kraken Confidence Scores for Reliable Domain-Specific Microbiota Inference and Discovery Version: 0.99.16 Authors@R: c( person("Thiago", "Parente", , email = "thiago.parente@fiocruz.br", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-7501-726X")), person("Fiocruz", role = "fnd"), person("IOC-Fiocruz", role = "fnd"), person("CAPES", role = "fnd")) Description: Provides a comprehensive framework for analyzing Kraken2 metagenomic classification using multiple confidence scores. karioCaS implements a robust comparative approach to evaluate taxonomic stability across different stringency levels, facilitating the identification of reliable microbiota components and the discovery of potentially novel or unrepresented species. A key innovation is its domain-specific analysis, separately processing Bacteria, Archaea, Eukaryota, and Viruses to ensure balanced visibility of all biological domains. Includes high-quality visualization tools for retention rates, shared taxa (Upset plots), and stability heatmaps. License: GPL (>= 3) Depends: R (>= 4.5.0) Encoding: UTF-8 RoxygenNote: 8.1.0 Imports: ggplot2, patchwork, UpSetR, dplyr, readr, stringr, tidyr, scales, ggtext, SummarizedExperiment, TreeSummarizedExperiment, S4Vectors, forcats, tibble, methods, rlang, grid, grDevices, stats, utils Suggests: BiocStyle, knitr, rmarkdown, testthat (>= 3.0.0) VignetteBuilder: knitr Config/testthat/edition: 3 biocViews: Metagenomics, Microbiome, DataImport, Software URL: https://github.com/thiagoparentefiocruz/karioCaS BugReports: https://github.com/thiagoparentefiocruz/karioCaS/issues Config/pak/sysreqs: cmake make libicu-dev libjpeg-dev libpng-dev libuv1-dev libxml2-dev libssl-dev libx11-dev zlib1g-dev Repository: https://biocstaging.r-universe.dev Date/Publication: 2026-09-28 19:20:14 UTC RemoteUrl: https://github.com/BiocStaging/karioCaS RemoteRef: HEAD RemoteSha: f2bbabd144ef4c6428e1c42253f83231c592ce6c NeedsCompilation: no Packaged: 2026-09-28 22:20:32 UTC; root Author: Thiago Parente [aut, cre] (ORCID: ), Fiocruz [fnd], IOC-Fiocruz [fnd], CAPES [fnd] Maintainer: Thiago Parente