NEWS
lantern 0.99.0
- Initial Bioconductor submission.
ancestry_split() splits a phased VCF into per-ancestry dosages using
RFMix local ancestry, in "haplotype" (phased) or "dosage" (unphased)
mode, for any number of populations. Dosage mode shrinks ambiguous
mixed-ancestry splits toward each chromosome arm's global ancestry.
write_ancestry_gds() / write_dosage_gds() write SeqArray GDS files.
ancestry_smmat() runs ancestry-stratified GMMAT SMMAT gene tests and
Cauchy-combines the per-ancestry p-values (cauchy_combine()).
- VCFs are read with
bcftools when it is on PATH, otherwise with
SeqArray. Choose one explicitly with options(lantern.vcf_reader = ...).
- Example dataset in
inst/extdata (simulated; see inst/scripts/make_toy_data.R).