Package: mgcca Type: Package Title: Generalized Canonical Correlation Analysis with Missing Individuals Version: 0.99.6 Date: 2026-10-02 Authors@R: c( person( given = "Dolors", family = "Pelegri-Siso", email = "dolors.pelegri@isglobal.org", role = c("aut", "cre"), comment = c(ORCID = "0000-0002-5993-3003")), person( given = "Isaac", family = "Subirana", role = c("aut")), person( given = "Juan R.", family = "Gonzalez", email = "juanr.gonzalez@isglobal.org", role = c("aut"), comment = c(ORCID = "0000-0003-3267-2146")) ) Description: Implements Generalized Canonical Correlation Analysis (GCCA) with missing individuals (whole missing rows; van de Velden and Bijmolt, 2006) for multi-block omics integration. The package operates directly on HDF5 matrices via the BigDataStatMeth C++ API to scale computations; R functions are thin wrappers around the C++ core. Depends: R (>= 4.5.0) Imports: BigDataStatMeth (>= 2.0.6), MASS, rlang (>= 1.1.0), withr, Rcpp (>= 1.0.6), ggplot2 (>= 3.4.0), ggthemes, impute, SummarizedExperiment, graphics, grDevices, grid, methods, stats, utils LinkingTo: Rcpp, RcppEigen, Rhdf5lib, BigDataStatMeth, BH Suggests: BiocStyle, knitr, rmarkdown, testthat (>= 3.0.0), MultiAssayExperiment, Biobase, wordcloud, GenomicRanges, IRanges, BiocGenerics, made4, RSpectra, GenomeInfoDb, curatedTCGAData, TCGAutils, TxDb.Hsapiens.UCSC.hg19.knownGene, org.Hs.eg.db SystemRequirements: GNU make, C++17 License: MIT + file LICENSE URL: https://isglobal-brge.github.io/mgcca/, https://github.com/isglobal-brge/mgcca, http://brge.isglobal.org BugReports: https://github.com/isglobal-brge/mgcca/issues biocViews: StatisticalMethod, DimensionReduction, PrincipalComponent, GeneExpression, Transcriptomics, Epigenetics, Metabolomics VignetteBuilder: knitr Config/testthat/edition: 3 Encoding: UTF-8 RoxygenNote: 7.3.3 NeedsCompilation: yes Config/pak/sysreqs: make libicu-dev zlib1g-dev Repository: https://biocstaging.r-universe.dev Date/Publication: 2026-10-03 11:29:27 UTC RemoteUrl: https://github.com/BiocStaging/mgcca RemoteRef: HEAD RemoteSha: 4476903d1eae19f5619cfb33732df3cd4035213d Packaged: 2026-10-03 14:05:12 UTC; root Author: Dolors Pelegri-Siso [aut, cre] (ORCID: ), Isaac Subirana [aut], Juan R. Gonzalez [aut] (ORCID: ) Maintainer: Dolors Pelegri-Siso