Package: multipletR Type: Package Title: Adaptive Detection of Human-Mouse Multiplets in PDX Single-Cell Data Version: 0.99.0 Authors@R: person("Alexandra", "Gerveni", email = "alexandra.gerveni@hotmail.com", role = c("aut", "cre"), comment = c(ORCID = "0009-0004-5428-5889")) Description: Detects human-mouse multiplets in patient-derived xenograft (PDX) single-cell RNA-seq data using an adaptive threshold method that does not assume a fixed species proportion. Takes a 10x CellRanger GEM classification file and returns the data with added multiplet classifications, with optional diagnostic plots and helpers to annotate a Seurat or SingleCellExperiment object with multiplet classifications or remove multiplets from it. License: MIT + file LICENSE Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.3 Imports: diptest, ggplot2, methods, patchwork, scales, SingleCellExperiment, stats, SummarizedExperiment, utils Suggests: Seurat, knitr, rmarkdown, testthat (>= 3.0.0) VignetteBuilder: knitr biocViews: SingleCell, RNASeq, Preprocessing, QualityControl, Transcriptomics URL: https://github.com/Alex05a/multipletR BugReports: https://github.com/Alex05a/multipletR/issues Config/testthat/edition: 3 Config/pak/sysreqs: zlib1g-dev Repository: https://biocstaging.r-universe.dev Date/Publication: 2026-07-14 21:41:08 UTC RemoteUrl: https://github.com/BiocStaging/multipletR RemoteRef: HEAD RemoteSha: 053f1b5922b993ef22856b6d2614a6f43b100eb9 NeedsCompilation: no Packaged: 2026-07-16 20:40:07 UTC; root Author: Alexandra Gerveni [aut, cre] (ORCID: ) Maintainer: Alexandra Gerveni