Package: paweh
Title: Power and Sample Size Analysis for Genetic Studies with
        Heterogeneity and Misclassification
Version: 0.99.0
Authors@R: 
    c(
      person(
        given = "Akil",
        family = "Anthony",
        email = "akilanthony19@gmail.com",
        role = c("aut", "cre"),
        comment = c(ORCID = "0009-0008-8813-8560")
      ),
      person(
        given = "Derek",
        family = "Gordon",
        role = "aut"
      )
    )
Description: Provides prospective power and minimum sample size
        necessary (MSSN) calculations for genetic and genomic
        association study design. Supported designs include
        case-control studies, transmission disequilibrium tests with
        affected-child trios, and single- and multivariate
        quantitative-trait studies. The package emphasizes selected
        departures from idealized assumptions, including locus
        heterogeneity and supported forms of genotype and phenotype
        misclassification. These factors can materially affect power
        and sample-size requirements but can be difficult to
        incorporate analytically. Published statistical-genetics
        methods are implemented in a reproducible, primarily parameter-
        and model-based framework with static visualizations and an
        optional Shiny dashboard for interactive exploration. The
        software supports prospective study planning; it does not
        perform downstream association testing.
License: MIT + file LICENSE
Encoding: UTF-8
URL: https://github.com/akilanthony/paweh,
        https://akilanthony.github.io/paweh/
BugReports: https://github.com/akilanthony/paweh/issues
biocViews: ExperimentalDesign, Genetics, GenomeWideAssociation,
        ShinyApps
Roxygen: list(markdown = TRUE)
Suggests: BiocStyle, knitr, plotly, rmarkdown, testthat (>= 3.0.0)
Config/testthat/edition: 3
Imports: bslib, ggplot2, mvtnorm, rlang, shiny, withr
VignetteBuilder: knitr
Config/roxygen2/version: 8.1.0
Config/pak/sysreqs: cmake make libuv1-dev zlib1g-dev
Repository: https://biocstaging.r-universe.dev
Date/Publication: 2026-09-17 13:18:55 UTC
RemoteUrl: https://github.com/BiocStaging/paweh
RemoteRef: HEAD
RemoteSha: 7a5ed7bdfcab9f9f63e7e260204058bfcadf9cce
NeedsCompilation: no
Packaged: 2026-09-17 18:29:55 UTC; root
Author: Akil Anthony [aut, cre] (ORCID:
    <https://orcid.org/0009-0008-8813-8560>),
  Derek Gordon [aut]
Maintainer: Akil Anthony <akilanthony19@gmail.com>