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# CITATION.cff file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "pdactrace" in publications use:'
type: software
license: MIT
title: 'pdactrace: Stage-Aware PDAC Atlas and Prospectively Frozen Tissue-to-Serum
  Biomarker Audit Framework'
version: 0.99.25
doi: 10.5281/zenodo.20068234
identifiers:
- type: doi
  value: 10.32614/CRAN.package.pdactrace
abstract: 'pdactrace implements a transparent, deterministic claim-audit framework
  for stage-aware pancreatic ductal adenocarcinoma (PDAC) tissue-to-blood biomarker
  evidence. It integrates per-stage trajectory matching across bulk RNA-seq, tissue
  proteomics, single-cell origin, serum proteomics, and pancreatitis context, with
  explicit anchor-enrichment evaluation against a curated external reference set.
  The framework comprises a 12-template competitive trajectory catalog, a 3-axis +
  2-gate reference score, an Evidence Math layer, TRACE-D tissue-to-serum directional
  evidence concordance, claim-tier classification, and weight-robustness and Pareto
  support audits. A prespecification layer supports freezing candidate scores, directions
  and a decision rule under a content hash before outcome labels are opened, with
  a distinct inconclusive terminal state when a frozen gate fails. Scope is deliberately
  PDAC-specific: the bundled atlas, the anchor reference set and every validated claim
  are PDAC, and no result is claimed for any other disease. Separately, no supervised
  classifier is trained or shipped, because validated non-circular early-detection
  ground truth is unavailable in PDAC.'
authors:
- family-names: Ko
  given-names: Jibeom
  email: rhwlqja1779@gmail.com
  orcid: https://orcid.org/0009-0002-8630-1973
preferred-citation:
  type: manual
  title: 'pdactrace: Stage-Aware PDAC Atlas and Prospectively Frozen Tissue-to-Serum
    Biomarker Audit Framework'
  authors:
  - family-names: Ko
    given-names: Jibeom
    email: rhwlqja1779@gmail.com
    orcid: https://orcid.org/0009-0002-8630-1973
  year: '2026'
  notes: R package version 0.99.25
  doi: 10.5281/zenodo.20068234
  url: https://doi.org/10.5281/zenodo.20068234
repository: https://biocstaging.r-universe.dev
repository-code: https://github.com/jibeomko/pdactrace
commit: 131aa2c00e8e02fb75eeb180d47927fbc16c0f82
url: https://github.com/jibeomko/pdactrace
date-released: '2026-09-28'
contact:
- family-names: Ko
  given-names: Jibeom
  email: rhwlqja1779@gmail.com
  orcid: https://orcid.org/0009-0002-8630-1973