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# CITATION.cff file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "splitTypeR" in publications use:'
type: software
license: Artistic-2.0
title: 'splitTypeR: Transcriptomic Classification using Mixture of Normal Distributions'
version: 0.99.9
doi: 10.32614/CRAN.package.splitTypeR
abstract: The splitTypeR package enables the classification of bulk transcriptomic
  samples using gene signature lists. For each signature, an enrichment score is first
  calculated for every sample with Bioconductor GSVA, and the uncertainty around each
  score is estimated through permutations of the samples. Values drawn from the sample-specific
  normal distributions are then pooled to fit a mixture of two normal distributions
  that represents the whole cohort. Each sample is finally tested against the distribution
  with the lower mean, and samples with a significantly higher score are assigned
  to the signature. Published gene signatures related to pancreatic ductal adenocarcinoma
  subtyping are also provided.
authors:
- family-names: Deschênes
  given-names: Astrid
  email: adeschen@hotmail.com
  orcid: https://orcid.org/0000-0001-7846-6749
- family-names: Belleau
  given-names: Pascal
  email: pascal_belleau@hotmail.com
  orcid: https://orcid.org/0000-0002-0802-1071
- family-names: Tuveson
  given-names: David A.
  email: dtuveson@cshl.edu
  orcid: https://orcid.org/0000-0002-8017-2712
repository: https://biocstaging.r-universe.dev
repository-code: https://github.com/adeschen/splitTypeR
commit: f19ea104fd7c0c822734497a6d723d10007e4d92
url: https://github.com/adeschen/splitTypeR
date-released: '2026-10-24'
contact:
- family-names: Deschênes
  given-names: Astrid
  email: adeschen@hotmail.com
  orcid: https://orcid.org/0000-0001-7846-6749