Package: epiPortrait 0.99.3
epiPortrait: Replicate-Aware Epigenomic Domain Profiling
Provides methods for replicate-aware quantitative phenotyping and comparison of epigenomic domains from normalized continuous signal tracks and per-sample native peak/domain calls (histone-mark ChIP-seq / CUT&Tag as the primary use case; also applicable to ATAC-seq-derived domains). It characterizes each shared genomic domain by integrated signal magnitude (Intensity), sample-specific native peak breadth geometry, and continuous within-domain signal architecture (SignalDispersion). Replicate-level evidence is retained and aggregated with specified support rules, enabling condition-specific classification of Intensity-Super, Breadth-Super, Dual-Super, Typical, or Uncertain domain states without using the consensus-domain width as the breadth caller. The package further supports condition transitions, continuous domain-width remodeling, signal quality control, genome-aware domain annotation with a three-level export (per-domain summary, per-domain-gene pair, and raw relationship detail), optional BEDPE contact evidence, expression-aware candidate-gene prioritization, differential domain analysis on continuous BigWig signal using limma, and result visualization.
Authors:
epiPortrait_0.99.3.tar.gz
epiPortrait_0.99.3.zip(r-4.7-any)epiPortrait_0.99.3.zip(r-4.6-any)epiPortrait_0.99.3.zip(r-4.5-any)
epiPortrait_0.99.3.tgz(r-4.6-any)epiPortrait_0.99.3.tgz(r-4.5-any)
epiPortrait_0.99.3.tar.gz(r-4.7-any)epiPortrait_0.99.3.tar.gz(r-4.6-any)
epiPortrait_0.99.3.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
epiPortrait/json (API)
| # Install 'epiPortrait' in R: |
| install.packages('epiPortrait', repos = c('https://biocstaging.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/zying106/epiportrait/issues
- example_se - Example Epigenetic Portrait Dataset
chipseqatacseqepigeneticscoveragenormalizationdifferentialexpressiongenomeannotationqualitycontrolvisualizationprincipalcomponent
Last updated from:6dd14984eb. Checks:1 NOTE, 9 OK. Indexed: yes.
| Target | Result | Time | Files | Syslog |
|---|---|---|---|---|
| bioc-checks | NOTE | 299 | ||
| linux-devel | OK | 515 | ||
| source / vignettes | OK | 384 | ||
| linux-release | OK | 518 | ||
| macos-release | OK | 448 | ||
| macos-oldrel | OK | 410 | ||
| windows-devel | OK | 410 | ||
| windows-release | OK | 428 | ||
| windows-oldrel | OK | 408 | ||
| wasm-release | OK | 269 |
Exports:analyze_differential_domainsannotate_epi_domainsbuild_portrait_matrixcall_super_domainscheck_signal_compatibilitycombine_superdomain_callscompare_superdomain_classescompare_superdomainscompute_width_transitionexport_epiportrait_resultsfilter_blacklistfilter_promoter_peaksfind_hockey_inflectionget_call_provenanceget_call_resultsget_combined_class_resultsget_consensus_peaksget_domain_genesget_domain_resultsget_mark_presetget_replicate_callsget_sample_resultsget_transition_resultsget_uncertain_causeintegrate_cross_marknormalize_portraitplot_class_transitionplot_differential_volcanoplot_domain_class_compositionplot_domain_feature_profileplot_domain_landscapeplot_hockey_stickplot_peak_trackplot_portrait_correlationplot_portrait_pcaplot_replicate_supportplot_uncertain_causesave_epiportrait_figurestitch_epi_peakssummarize_epiportrait_objecttransition_matrix_per_samplevalidate_epiportrait_object
Dependencies:abindAnnotationDbiaskpassBHBiobaseBiocBaseUtilsBiocGenericsBiocIOBiocParallelBiostringsbitbit64bitopsblobcachemcigarilloclicodetoolscpp11crayoncurlDBIDelayedArraydigestfarverfastmapformatRfutile.loggerfutile.optionsgenericsGenomeInfoDbGenomicAlignmentsGenomicFeaturesGenomicRangesggplot2ggrepelgluegtablehttrIRangesisobandjsonliteKEGGRESTlabelinglambda.rlatticelifecyclelimmaMatrixMatrixGenericsmatrixStatsmemoisemimeopensslpkgconfigpngR6RColorBrewerRcppRCurlrestfulrRhtslibrjsonrlangRsamtoolsRSQLitertracklayerS4ArraysS4VectorsS7scalesSeqinfosnowSparseArraystatmodSummarizedExperimentsysUCSC.utilsvctrsviridisLitewithrXMLXVectoryaml
